A severe epilepsy syndrome with triad of infantile spasms, an interictal electroencephalogram (EEG) pattern termed hypsarrhythmia, and mental retardation.
X-linked InfantileSpasmsSyndrome (ISSX) is a catastrophic epilepsy of early childhood with intractable seizures, intellectual disability, and poor prognosis.
1
Reports on the use of topiramate for treatment of infantilespasms are limited.
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Seizure types were variable, including infantilespasms and myoclonic seizures, and often prolonged.
3
Twelve patients had symptomatic infantilespasms, and two patients had cryptogenic infantilespasms.
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This study evaluated the efficacy and safety of vigabatrin for Japanese patients with infantilespasms.
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We encountered two WBS patients presenting with infantilespasms, which is extremely rare in WBS.
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On screen, Margrit finished her beer and drank Cole's in epilepticspasms.
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Main seizure types were epilepticspasms in 17 patients and tonic spasms in eight.
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Conclusion: This study demonstrated that serial EEG findings after ACTH therapy are significantly related to relapse of epilepticspasms.
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Background: Corpus callosotomy (CC) has recently been adopted for the treatment of drug-resistant epilepticspasms and tonic spasms.
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The patient was admitted due to infantile epilepticspasms at eight months of age, motor developmental delay, and dysmorphic features.
1
Reports on the use of topiramate for treatment of infantilespasms are limited.
2
Seizure types were variable, including infantilespasms and myoclonic seizures, and often prolonged.
3
Twelve patients had symptomatic infantilespasms, and two patients had cryptogenic infantilespasms.
4
This study evaluated the efficacy and safety of vigabatrin for Japanese patients with infantilespasms.
5
We encountered two WBS patients presenting with infantilespasms, which is extremely rare in WBS.
1
Results: We used iobio to identify the disease-causing variant in a patient with early infantileepilepticencephalopathy with prior nondiagnostic genetic testing.
Uso de west syndrome en inglés
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We retrospectively studied 18 patients with Westsyndrome treated with ACTH according to Fukuyama's method.
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We experienced one symptomatic case and three cryptogenic cases of Westsyndrome that showed spontaneous remission.
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Of these, 3 had Westsyndrome.
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Generally, Westsyndrome is an intractable epileptic syndrome in infancy, although spontaneous remission has been reported in some cases.
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Here, we report a patient with Westsyndrome whose chromosome analysis revealed 14q11.2-21.1 duplication.
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An immunologic response to infection might be one of the factors involved in the remission of Westsyndrome, but the mechanisms remain unknown.
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Our results suggest that choice of drug in the initial treatment of Westsyndrome should be determined by clinical features (especially etiology).
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The changes in serum antibody values suggest that the spontaneous remission of Westsyndrome was related to human herpesvirus 6 and 7 infections.